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    <lastmod>2024-11-22</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/donate</loc>
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    <lastmod>2026-03-20</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/projects</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2026-03-14</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/c4d318ef-6260-41e1-8d74-20c396b0153a/Email+-+Rapa.png</image:loc>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442486356-SXX9BUYGNHJ0ROLWBAUY/Blood-Test-Tubes.jpg</image:loc>
      <image:title>Projects - Project: Mouse models and molecular studies to test pathway dysfunction and treatment possibilities. Collaboration: University of Wisconsin Milwaukee, Milwaukee Institute of Drug Discovery, Coppe Laboratories</image:title>
      <image:caption>This group of projects will utilize Simmaron’s new Research and Development Laboratory in collaboration with Coppe Lab and University of Wisconsin’s animal research facility. These studies aim to identify broken pathways in energy production in ME/CFS, long-COVID and POTS, test interventions at a molecular level, and explore mouse models critical to drug discovery and treatments.   Funding goal: $500,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1601249515762-2DM9AYKA09TZETPDPG6T/SRI_034.jpg</image:loc>
      <image:title>Projects - Project: Seahorse I  Collaboration: Cornell University</image:title>
      <image:caption>This project aims to take a multi-omics approach to understand differences in isolated immune cells collected from ME/CFS patients and healthy controls. The aim of this project is to help researchers in the field better understand phenotyping different subsets of ME/CFS patients.  Funding goal: $75,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1605754939315-L6LHLVT0ZUSN5LX4GL91/SRI_049.jpg</image:loc>
      <image:title>Projects - Project: The Development of Patient Derived Induced Pluripotent Stem Cells (IPSCs) from Skin Fibroblasts and Peripheral Blood Mononuclear Cells—Modeling Drug Response* Collaboration: Avik Roy Ph.D., C. Gunnar Gottschalk Ph.D.</image:title>
      <image:caption>Induced pluripotent stem cells (IPSCs) are cells that have been genetically reprogrammed to an embryonic stem cell–like state by being forced to express genes and factors important for maintaining the defining properties of embryonic stem cells. IPSCs can be further cultured to express the phenotype of any cell residing in either the periphery or central nervous system. Recently, we have developed a protocol to isolate IPSCs from easily accessible whole blood and skin fibroblasts samples taken in the clinic. Following isolation, IPSCs can be immortalized prior to further differentiation. The downstream differentiation of IPSCs into the cells relevant to a disease phenotype provides a non-invasive mechanism for personalized drug screening investigations, and complimentary studies aimed to understand the role of functional genomics, proteomics and metabolomics within that individual. Using this tool, we recently described for the first time the functional role of a homozygous BPOZ-2-point mutation as it relates to the development of Parkinson’s Disease in a severely affected pediatric patient. IPSC technology is slated to be the future of personalized medicine, and its implementation in the field of ME/CFS is both novel and critical. Funding goal: $100,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1601250139510-XZX46U9F6LJH9XGP7NAI/SRI_001.jpg</image:loc>
      <image:title>Projects - Project: AMP-Nano* Collaboration: Cornell University</image:title>
      <image:caption>In this prospective, longitudinal study we aim to identify why some ME/CFS patients respond to specific intravenous therapies provided by our clinical partner. Our primary goal is to identify phenotypic responders to therapies and develop a treatment algorithm that can be shared with other clinicians in the field of ME/CFS patient care. Funding goal: $150,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1601250084466-HAVYYJ9YGJIKZ9N9LWD9/SRI_009.jpg</image:loc>
      <image:title>Projects - Project: Red AMP* Collaboration: Centers for Disease Control</image:title>
      <image:caption>In this retrospective, longitudinal study we are analyzing both unstructured patient medical records from our clinical partner and structured case report folders derived from the Ampligen® 511 Phase III clinical trial. With the help of partners at CDC, we aim to 1) validate our responder cohort and 2) to identify surrogate clinical makers of response to Ampligen® therapy. Funding goal: $100,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1601250393779-UYCKPEFENG2Z5TCRUSYQ/SRI_029.jpg</image:loc>
      <image:title>Projects - Project: Whole exome sequencing of families suffering from ME/CFS Collaboration: Open Medicine Foundation, Stanford University</image:title>
      <image:caption>This project involves collecting DNA samples from families that have multiple lineages of ME/CFS. We aim to compare individuals within families that are both affected and non-affected, potentially enabling identification of novel genetic aberrations. Funding goal: $75,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1601306199047-RUQ6WO9YTOIVAO6YP22O/SRI_006.jpg</image:loc>
      <image:title>Projects - Project: Assessment of 25 bone marrow biopsies from ME/CFS patients and healthy controls harboring B-cell clonal rearrangements Collaboration: Stanford University</image:title>
      <image:caption>Over the past 3 years our team has collected bone marrow samples from ME/CFS patients and others with b-cell clonal rearrangement. B-cell clonal rearrangements account for a significant number of lymphomas diagnosed in ME/CFS patients in Dr. Peterson’s clinic. We aim to analyze marrow tissue at the molecular level to identify the driving force behind this extremely dangerous immune perturbation. Funding goal: $150,000</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1605754864448-G08BSHKEEC1GS1Z7ILGV/SRI_024.jpg</image:loc>
      <image:title>Projects - Project: HLA typing in ME/CFS families  Collaboration: University of Montreal</image:title>
      <image:caption>Human Leukocyte Antigen (HLA) typing allows categorization of the protein receptors on immune cells. Multiple studies have reported that ME/CFS patients’ HLA types cluster into groups that are different than unaffected individuals. Using HLA technology, we aim to better understand the potential genetic predisposition for the immune dysfunction observed in ME/CFS patients. Funding goal: $100,000</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/publications</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2026-03-14</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog</loc>
    <changefreq>daily</changefreq>
    <priority>0.75</priority>
    <lastmod>2024-12-18</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/simmaron-partners-with-agelessrx</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2024-11-27</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/p62lvex5rqx2lvxtluymrl6ipy7dzh</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2024-11-22</lastmod>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/f8cc4da1-eb47-4a39-8ddd-a28bfbafed07/BBC+article+image+smaller.png</image:loc>
      <image:title>Simmaron Rising: Blog - BBC article features Simmaron! - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1732248256755-RACK1ARPMPA2TCJKVQUL/POST1-Making+Moves.png</image:loc>
      <image:title>Simmaron Rising: Blog - BBC article features Simmaron!</image:title>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1732248284311-XP2MM6WJ60VBR2LUX6GR/TY+Clinicians+3.png</image:loc>
      <image:title>Simmaron Rising: Blog - BBC article features Simmaron!</image:title>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/our-new-publication-details-findings-on-high-bh4-in-an-me-subset</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2024-11-02</lastmod>
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      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/d36ae7e8-c3c9-46f6-9f0c-b7ea04f8f94c/BH4BH2+Hypoxia+smaller.png</image:loc>
      <image:title>Simmaron Rising: Blog - Our new publication details findings on high BH4 in an ME subset! - Why do ME patients with Orthostatic Intolerance have elevated BH4?</image:title>
      <image:caption>Can our new findings lead to potential targets for treating OI?</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/watch-simmaron-at-invest-in-me</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2024-10-19</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/do-you-want-to-learn-more-about-mouse-models</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2023-10-08</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/19117eb5-344e-4c2b-860d-ed3a487209d0/mice+pem+pots+brain.png</image:loc>
      <image:title>Simmaron Rising: Blog - Do you want to learn more about mouse models in ME/CFS? - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/50fd63a9-3f44-4b7b-9914-d1f278b476e6/mouse+model+proxies+for+CFS+slide.jpeg</image:loc>
      <image:title>Simmaron Rising: Blog - Do you want to learn more about mouse models in ME/CFS? - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/59b623be-b9ed-4287-a736-add8b97419dd/mouse+model+shortcomings+slide.jpeg</image:loc>
      <image:title>Simmaron Rising: Blog - Do you want to learn more about mouse models in ME/CFS? - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/dfd55268-5eaa-4282-8c82-533a9705c511/mouse+model+overview+mentions+simm+cropped.jpeg.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Do you want to learn more about mouse models in ME/CFS? - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/simmaron-wins-our-1st-nih-grant</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2023-04-30</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/43c3f435-654e-4de5-888d-069650748d33/NIH-Award.png</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Wins our 1st NIH Grant! - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/be42a960-41cd-4926-90ec-7227a4a6744e/POST5-+ATG-13+Diagram.png</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Wins our 1st NIH Grant! - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/2d90a0dc-5e81-4eb3-ab2b-6625dddcdc5b/NetworkForGood.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Wins our 1st NIH Grant! - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/nih-directors-blog-features-columbia-study-with-simmaron</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2023-03-05</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/abb70131-c742-4c4b-910f-3575d2e0a301/NIH+Directors+blog+image+gut-microbiome-1536x864+021423.png</image:loc>
      <image:title>Simmaron Rising: Blog - NIH Director’s blog features Columbia study with Simmaron! - Make it stand out</image:title>
      <image:caption>More Clues into ME/CFS Discovered in Gut Microbiome Posted on February 14th, 2023 by Lawrence Tabak, D.D.S., Ph.D. https://directorsblog.nih.gov/2023/02/14/more-clues-into-me-cfs-discovered-in-gut-microbiome/</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/cleaning-crisis-is-defective-mitochondrial-cleanup-in-mecfs-may-be-impairing-energy-production</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-09-18</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/5291e00c-0e15-4d18-82c5-d02854fa24d1/Mitochondria_Medical-gallery-of-Blausen-Medical-2014_Blausen_0644_Wikimedia_Commons.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Cleaning Crisis? Is Defective Mitochondrial Cleanup  Impairing Energy Production in ME/CFS? - Make it stand out</image:title>
      <image:caption>Something appears to be going on with the mitochondria bu exactly what is unclear. (from Blausen 2014 Medical Gallery - Wikimedia Commons).</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/4ebfa197-03d3-40cd-9dd7-911f6fa26ecd/Cleaning_Istockphoto.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Cleaning Crisis? Is Defective Mitochondrial Cleanup  Impairing Energy Production in ME/CFS? - Make it stand out</image:title>
      <image:caption>Could broken cleanup processes be impairing energy production in ME/CFS?</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/42a15d6c-58c7-4a05-9575-6d751c2d7b7d/Autophagy_Sadafjavaidkhan_Wikimedia_Commons.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Cleaning Crisis? Is Defective Mitochondrial Cleanup  Impairing Energy Production in ME/CFS? - Make it stand out</image:title>
      <image:caption>Impaired autophagy could be inhibiting energy production, send cells into a stupor, and cause them to start emitting pro-inflammatory substances.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/seeing-mecfs-creating-the-first-mouse-models-for-the-disease</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-05-12</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/2a91eb5a-b43d-4f3e-a671-b1163acd9602/Eyes-research.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Seeing ME/CFS: Creating the First Mouse Models for the Disease - Make it stand out</image:title>
      <image:caption>The goal: enable researchers to see and better understand ME/CFS by creating an ME/CFS mouse model.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/aa0b4cb6-3671-4b63-af81-5f232ac815ae/Animal-studies.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Seeing ME/CFS: Creating the First Mouse Models for the Disease - Make it stand out</image:title>
      <image:caption>Mouse models play an important role in medical research and drug development. The creation of a Gulf War Illness mouse model, for instance, provided novel insights and supported the development of a large clinical trial</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/04dedf84-69fa-43ad-b842-d4d8525f3939/ATG13-Inactivation-Mouse_Model_Simmaron.gif</image:loc>
      <image:title>Simmaron Rising: Blog - Seeing ME/CFS: Creating the First Mouse Models for the Disease - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/3103c878-06ae-408a-ab0a-181b6da54936/DNA-discoveries.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Seeing ME/CFS: Creating the First Mouse Models for the Disease - Make it stand out</image:title>
      <image:caption>Producing a “transgenic” ME/CFS mouse model; i.e. mouse into which human genes have been added is next.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/26c02058-81b9-4601-a698-87c24096ef87/Simmaron_Donate_Button.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Seeing ME/CFS: Creating the First Mouse Models for the Disease - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/covid-19-keptide-ace2-chronic-fatigue-simmaron</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2023-02-01</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1633891263205-8X0E6ZCZTVXNCKJIJFFC/Gunnar%2Bcropped.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team</image:title>
      <image:caption>Gunnar Gottschalk returned from medical school with a Ph.D., a new partner, and a new set of skills.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1633895866023-VG2XA3TMDI9SZH9MFCNA/Avik+Roy.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team</image:title>
      <image:caption>Avik Roy’s interests in inflammation, the mitochondrial stress response, and cognition led him to ME/CFS and Simmaron.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1634233726115-7638LHNSF94358WMZ5DY/Coronavirus-CDC-2020.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team - Make it stand out</image:title>
      <image:caption>Cell and animal studies suggest the keptide may be able to block the coronavirus from attaching to the ACE-2 receptors on our cells</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1634234094606-ZQ7HELHTDM3SCN8G8UFA/Breakthrough-new-realm.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team - Make it stand out</image:title>
      <image:caption>The finding that the virus may be able produce substantial pathology without actually infecting cells potentially opens a new window on our understanding of how the virus causes harm.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1634234755728-6JTCM4E8SRZKROAV9PEN/We-Have-Ideas.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team - Make it stand out</image:title>
      <image:caption>Innovation and creativity have been hallmarks of the Simmaron Foundation’s new research efforts.</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1634309886094-QFJZY5NY7WCLQKBFFVZ2/Simmaron_Donate_Button.png</image:loc>
      <image:title>Simmaron Rising: Blog - Innovation - A Hallmark of Simmaron’s New Research Team - Make it stand out</image:title>
      <image:caption>Whatever it is, the way you tell your story online can make all the difference.</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/09/lipkin-long-hauler-coronavirus-b-cells-biomarkers-chronic-fatigue-syndrome</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2023-02-01</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510765-41ELASB66HG3Z0IG3N1I/lipkin-coronavirus.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Ian Lipkin on Long Hauling with the Coronavirus, a Possible B-cell Subset, and Protein Biomarkers for ME/CFS</image:title>
      <image:caption>Ian lipkin coronavirus</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510655-9TL9DHWEORYK90NR9FSE/antibodies-III.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Ian Lipkin on Long Hauling with the Coronavirus, a Possible B-cell Subset, and Protein Biomarkers for ME/CFS</image:title>
      <image:caption>Immunoglobulin</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510467-B4XJ3A1RDR1ACGX11KNJ/IGF1_.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Ian Lipkin on Long Hauling with the Coronavirus, a Possible B-cell Subset, and Protein Biomarkers for ME/CFS</image:title>
      <image:caption>IGF-1</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510572-3NBHV6ERMMHTTUSRQZKK/abdomen-woman.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Ian Lipkin on Long Hauling with the Coronavirus, a Possible B-cell Subset, and Protein Biomarkers for ME/CFS</image:title>
      <image:caption>Gut flora</image:caption>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/07/old-drug-epstein-barr-virus-spironolactone</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-09-19</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510158-M3932VT57LL5R8V90KN5/Reactivated_Virus_CFS.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Old Drug Points To a New Way To Knock the Epstein-Barr Virus Down</image:title>
      <image:caption>EBV Reactivation</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442510357-5Q2UW2ZL4OJYCSAEMC1G/Spironolactonone_Aldactone_125mg_vials_yellow_background.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Old Drug Points To a New Way To Knock the Epstein-Barr Virus Down</image:title>
      <image:caption>aldactone - spironolactone</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442506858-KI9W9OKWWPQ4LNY5K19Y/Epstein_Barr_Virus_virions_round_circles.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Old Drug Points To a New Way To Knock the Epstein-Barr Virus Down</image:title>
      <image:caption>EBV virions</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442241426-LU9M2ZJXOCKTTJGESXPZ/SR_Donate_6.9.14_51.png</image:loc>
      <image:title>Simmaron Rising: Blog - Old Drug Points To a New Way To Knock the Epstein-Barr Virus Down</image:title>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/07/active-epstein-barr-infections-found-in-large-me-cfs-study</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-09-19</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/06/covid-19-tahoe-outbreak-peterson</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2021-10-10</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/05/blood-vessel-crunch-chronic-fatigue-syndrome</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-09-19</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442502781-1JUZP28S8Q758Y2SB8LU/B2AdR.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
      <image:caption>B2AdR</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442458267-7SX7YACXPVG5TH660NAR/Scheibenbogen_Carmen-From-Invest-in-ME.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
      <image:caption>Scheibenbogen</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442503192-0H9F6Y7OX7JFRRLGX3GO/RAAS_Wikimedia.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
      <image:caption>RAAS - Wikimedia</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442502959-R1YE65WVHATLPL4XEXQZ/Bradykinin.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
      <image:caption>bradykinin</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442506483-EM5EHJKKYMNMHSOPXYSB/Wirth-Klaus.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
      <image:caption>A local TV report triggered Klaus Wirth's interest in ME/CFS</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442241341-4H3ABW5P3Y846FT65292/SR_Donate_6.9.14_5.png</image:loc>
      <image:title>Simmaron Rising: Blog - The Blood Vessel Crunch: A Unifying Hypothesis for ME/CFS</image:title>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/05/immune-battle-chronic-fatigue-syndrome-herpesviruses-regulatory-t-cell</loc>
    <changefreq>monthly</changefreq>
    <priority>0.5</priority>
    <lastmod>2022-09-19</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/04/will-covid-19-leave-an-explosion-of-me-cfs-cases-in-its-wake</loc>
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    <priority>0.5</priority>
    <lastmod>2023-02-01</lastmod>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442503257-57I367WKGXGMWPK9D9Z1/SARS_Coronaviruses_2004.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Will COVID-19 Leave An Explosion of ME/CFS Cases in its Wake?</image:title>
      <image:caption>SARS CoV</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442504258-DMPIGEC21WEULFWUW5OO/obscured-image.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Will COVID-19 Leave An Explosion of ME/CFS Cases in its Wake?</image:title>
      <image:caption>SARS patients unable to work</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442503061-YL1ZY5LY4YK2N3JNQS5N/Coronavirus_SARS-CoV-2_Electron_microscope.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Will COVID-19 Leave An Explosion of ME/CFS Cases in its Wake?</image:title>
      <image:caption>SARS-CoV-2 virions</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442241426-LU9M2ZJXOCKTTJGESXPZ/SR_Donate_6.9.14_51.png</image:loc>
      <image:title>Simmaron Rising: Blog - Will COVID-19 Leave An Explosion of ME/CFS Cases in its Wake?</image:title>
    </image:image>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/03/simmaron-celebrates-ten-years-of-innovative-research</loc>
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    <priority>0.5</priority>
    <lastmod>2020-11-24</lastmod>
    <image:image>
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      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
      <image:caption>Dr. Peterson</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442406168-VY8XO8LWW0IBGPD19DMM/CSF-Brain.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
      <image:caption>A gateway to the brain - the cerebral spinal fluid</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442502363-F21ODKGOTG86KXVF9CWD/Subsets-cfs.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
      <image:caption>Peterson subset</image:caption>
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    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442502565-AIXGBNBC7JW5LRD93CEM/abdomen-woman.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
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    <image:image>
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      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
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    <image:image>
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      <image:title>Simmaron Rising: Blog - Simmaron Celebrates Ten years of Innovative ME/CFS Research</image:title>
      <image:caption>Simmaron</image:caption>
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  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2020/01/lipkin-serochip-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2020-01-01</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/12/naltrexone-natural-killer-cells-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2019-12-19</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/11/inflammation-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2019-11-25</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/11/pathways-fine-tuning-treatments-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2019-11-22</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/10/better-lyme-diagnostic-nih-strategic-plan</loc>
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    <priority>0.5</priority>
    <lastmod>2019-10-22</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/08/me-cfs-seahorse-energy-production-study-shows-surprises</loc>
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    <priority>0.5</priority>
    <lastmod>2021-10-10</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/08/fecal-transplant-chronic-fatigue-study-promise</loc>
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    <priority>0.5</priority>
    <lastmod>2019-08-24</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/07/epstein-barr-virus-neuroinflammation-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2019-07-03</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/06/epstein-barr-virus-ebv-genes-chronic-fatigue-syndrome</loc>
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    <priority>0.5</priority>
    <lastmod>2019-06-29</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/05/mait-cell-findings-unite-us-uk-chronic-fatigue-syndrome-me-cfs-research</loc>
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    <priority>0.5</priority>
    <lastmod>2019-05-26</lastmod>
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    <loc>https://www.simmaronresearch.com/blog/2019/04/help-simmaron-amplify-therapies-for-m-e</loc>
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    <priority>0.5</priority>
    <lastmod>2019-04-23</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/04/nath-chronic-fatigue-syndrome-east-african-disease-model</loc>
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    <priority>0.5</priority>
    <lastmod>2019-04-02</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/03/doctor-nih-chronic-fatigue-intramural-study</loc>
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    <priority>0.5</priority>
    <lastmod>2019-03-25</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/03/nath-intramural-chronic-fatigue-study</loc>
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    <priority>0.5</priority>
    <lastmod>2019-03-23</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/03/the-brainstem-vagus-nerve-neuroinflammation-and-chronic-fatigue-syndrome-the-vanelzakker-way</loc>
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    <priority>0.5</priority>
    <lastmod>2019-03-19</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/02/coffi-fatigue-infection-me-cfs</loc>
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    <priority>0.5</priority>
    <lastmod>2019-02-23</lastmod>
  </url>
  <url>
    <loc>https://www.simmaronresearch.com/blog/2019/01/gut-cure-neuroinflammation-m-s-mecfs-inquiry</loc>
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    <priority>0.5</priority>
    <lastmod>2019-01-27</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2018/12/immune-factor-jump-start-chronic-fatigue-syndrome-me</loc>
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    <priority>0.5</priority>
    <lastmod>2018-12-31</lastmod>
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  <url>
    <loc>https://www.simmaronresearch.com/blog/2018/12/probiotic-paradox-probiotics-fail-even-harm-mecfs-perspective</loc>
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    <lastmod>2018-12-18</lastmod>
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    <image:image>
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      <image:title>Simmaron Rising: Blog - Big Antiviral Trial Could Usher in New Treatment Era for Fibromyalgia</image:title>
      <image:caption>woman questioning</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442282740-UZP53G2V88ZMQRB1TS4Q/Viral-Attack-CFS.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Big Antiviral Trial Could Usher in New Treatment Era for Fibromyalgia</image:title>
      <image:caption>virus</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442277637-6FGHGPFA32Z8K0UT4077/Connections-300x211.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Big Antiviral Trial Could Usher in New Treatment Era for Fibromyalgia</image:title>
      <image:caption>connections</image:caption>
    </image:image>
    <image:image>
      <image:loc>https://images.squarespace-cdn.com/content/v1/5f089a2e0e4f1254b66e2bc9/1602442286430-7H58AM80ZX1JKBTF0W0H/breakthroughII.jpg</image:loc>
      <image:title>Simmaron Rising: Blog - Big Antiviral Trial Could Usher in New Treatment Era for Fibromyalgia</image:title>
      <image:caption>breakthrough arrow</image:caption>
    </image:image>
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